When people use long-term antibiotics for any treatment it will lead to the delay in brain function and affect the formation of new brain cells says a study. In between gut and the brain, there is a special immune cell serves as an intermediary according to Susanne Wolf from Max Delbruck Centre for Molecular Medicine in Germany.
When it comes to effects of using antibiotics it could also help to alleviate the symptoms to mental disorders. says researchers. Using hormones, metabolic products and neural connections the gut and the brain talk to one another.
In reference with the mice that undergone treatment with gut microbiome switched off, they observed fewer newly formed nerve cells in the hippocampus region of the brain. Because of the formation of these brain cells, the mice is treated in its memory which is a process called neurogenesis for certain memory functions.
When the mice are stopped giving these antibiotic cells, neurogenesis declined and when the antibiotics are given to mice neurogenesis is increased once again says the researchers.
There are two strategies that the cured mice uses the mice were either given a selected bacterial strains or had access to voluntary training in running wheel and reversing the negative effects of antibiotics.
“With the Ly6C(hi) monocytes, we may have discovered a new general communication path from the periphery to the brain,” said Ms. Wolf.
“It is possible, however, that similar effects could result from treatments involving long-term use of antibiotics,” said Ms. Wolf.
When these are applied to humans the finding will not show all antibiotics disrupt brain function as the combination of drugs in the study which is extremely potent said the researchers.